How Long Does Zopiclone Stay in Your System?

If you’ve taken Zopiclone for sleep and wondered how long it remains in your body, you’re not alone. Many people across the UK ask this question, especially when thinking about next-day drowsiness, driving, work commitments, or drug testing.

Zopiclone is designed to help with short-term insomnia, but its effects don’t always disappear as soon as you wake up. Understanding how long Zopiclone takes to work and wear off can help you use it more safely and confidently.

What Happens After You Take Zopiclone?

Once swallowed, Zopiclone is absorbed into the bloodstream relatively quickly. Most people begin to feel sleepy within 30 to 60 minutes, which is why it’s usually taken immediately before bed.

The medication works by slowing activity in the brain, promoting relaxation and making it easier to fall asleep. While the strongest effects occur during the night, smaller amounts of the drug may still be present in your system the following day.

Zopiclone Half-Life Explained

The half-life of a medication refers to the time it takes for half of the drug to be eliminated from the body. Zopiclone has an average half-life of around five hours in healthy adults.

This means that after five hours, about 50% of the drug remains in your system. After another five hours, that amount halves again. Although the sedative effects may wear off sooner, traces can linger longer.

How Long Does Zopiclone Stay in Your System Overall?

In most cases, Zopiclone is largely cleared from the body within 24 hours. However, this doesn’t mean everyone will feel completely back to normal by morning.

Some people may experience lingering effects such as grogginess or slower reaction times, particularly if they are sensitive to sleep medications or didn’t get a full night’s rest.

Factors that influence how long Zopiclone stays in your system include age, liver function, dosage, and whether it’s taken alongside other medications.

Read More: why Zopiclone may not work as expected

Detection Times: Can Zopiclone Show Up in Tests?

Zopiclone is not commonly included in standard workplace drug tests. However, specialised screenings can detect it for a limited period.

Test TypeApproximate Detection Time
Blood TestUp to 24 hours
Urine Test24–48 hours
Saliva TestUp to 24 hours

Detection times can vary depending on dosage and individual metabolism. If drug testing is a concern, it’s important to inform healthcare professionals about any prescribed sleep medication.

Next-Day Drowsiness and Driving Safety

Even though Zopiclone is usually taken at night, next-day drowsiness can occur, particularly if the full recommended sleep time isn’t achieved.

UK guidance stresses caution when driving the morning after taking sleep medication. If you feel drowsy, dizzy, or unfocused, you should avoid driving altogether.

This is explained further in guidance on Zopiclone and driving safety in the UK, which outlines legal responsibilities and safety advice.

Factors That Affect How Long Zopiclone Stays in Your Body

Not everyone processes Zopiclone at the same speed. Several factors can influence how long it remains active:

  • Age: Older adults often eliminate the drug more slowly
  • Dosage: Higher doses take longer to clear
  • Liver health: Reduced liver function slows breakdown
  • Other medications: Some drugs interact with Zopiclone

Those taking medications for anxiety or pain should be especially cautious. This article on Zopiclone and anxiety-related sleep problems explains how overlapping effects can occur.

Read More: Zopiclone and lorazepam interaction

Does Zopiclone Build Up in the Body?

Zopiclone is not intended for long-term use. When taken nightly for extended periods, it can build up slightly in the body, increasing the risk of side effects.

This is one reason UK healthcare providers recommend short treatment courses, usually no longer than two to four weeks.

The NHS guidance on Zopiclone highlights the importance of using the lowest effective dose for the shortest possible time.

How to Help Zopiclone Leave Your System Safely

There’s no safe way to “flush” Zopiclone out of your system quickly, but healthy habits can support normal drug clearance:

  • Stay hydrated
  • Avoid alcohol
  • Get a full night’s sleep after taking it
  • Do not take extra doses

Never attempt to speed up elimination by taking other substances, as this can increase health risks.

Frequently Asked Questions

Can Zopiclone still affect me the next day?

Yes. Some people feel drowsy or less alert the following morning, especially if they slept less than seven hours.

Is it safe to take Zopiclone every night?

No. It’s intended for short-term use only due to the risk of dependence and reduced effectiveness.

Does food affect how long Zopiclone stays in your system?

A heavy meal before taking it may delay absorption slightly, but it doesn’t significantly change how long it stays in the body.

Key Takeaways for UK Users

Zopiclone typically stays in your system for up to 24 hours, though its main sleep-inducing effects wear off much sooner. Individual factors such as age, dosage, and overall health play a major role in how long it lingers.

If you’re considering treatment options, trusted sources such as Zopiclone 7.5mg tablets can provide consistent dosing when used responsibly.

Read More: when to take Zopiclone before bed

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